Preheat your oven to 400°F (200°C). Line a baking sheet with aluminum foil and place a wire rack on top.
In a large bowl, combine the chicken wings, salt, black pepper, garlic powder, onion powder, and smoked paprika. Toss until the wings are evenly coated with the spices.
Arrange the seasoned wings in a single layer on the wire rack. Bake in the preheated oven for 40-45 minutes, flipping halfway through, until the wings are crispy and golden brown.
While the wings are baking, melt the butter in a small saucepan over medium heat. Add the hot sauce, grated Parmesan cheese, and minced garlic. Stir until well combined and heated through.
Once the wings are done baking, transfer them to a large bowl. Pour the garlic Parmesan sauce over the wings and toss to coat evenly.
Serve immediately, garnished with chopped parsley if desired.