Preheat Oven: Set your oven to 400°F (200°C). Lightly grease a 9×13-inch baking dish with non-stick cooking spray.
Prepare Honey Mustard Mixture: In a small bowl, whisk together melted butter, honey, Dijon mustard, and minced garlic until well combined.
Season Salmon: Pat dry the salmon fillets and season both sides with salt and black pepper. Place them skin-side down in the prepared baking dish.
Apply Sauce: Generously spoon the honey mustard mixture over the salmon fillets, ensuring they are well coated.
Bake: Place the baking dish in the preheated oven and bake for 11–14 minutes, or until the salmon is flaky, pink, and opaque.
Garnish and Serve: Optionally, garnish with fresh parsley and serve with lemon wedges.