Preheat your oven to 425°F (220°C). Line a baking sheet with parchment paper and lightly spray it with cooking spray or drizzle with olive oil.
Set up a breading station: Place the flour in one shallow bowl, beat the eggs in a second bowl, and combine the breadcrumbs, garlic powder, paprika, salt, black pepper, and cayenne pepper in a third bowl.
Dredge each fish strip in the flour, shaking off the excess. Dip it into the beaten eggs, then coat it with the breadcrumb mixture, pressing gently to adhere.
Arrange the breaded fish sticks on the prepared baking sheet in a single layer. Lightly spray the tops with cooking spray or drizzle with olive oil for extra crispiness.
Bake in the preheated oven for 12-15 minutes, or until the fish is cooked through and the coating is golden brown and crispy. Flip the fish sticks halfway through baking for even crispiness.
Serve hot with lemon wedges on the side for squeezing over the fish sticks.